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Histology image: 22201loa – Histology Learning System at Boston University - "Ultrastructure of the Cell: chief cells and enteroendocrine cell" Histology image: 11304loa – Histology Learning System at Boston University - "Digestive System: Alimentary Canal: fundic stomach, gastric glands, base" "chief cell" at Dorland's Medical Dictionary
Fundic gland polyposis is a medical syndrome where the fundus and the body of the stomach develop many fundic gland polyps. The condition has been described both in patients with familial adenomatous polyposis (FAP) and attenuated variants (AFAP), and in patients in whom it occurs sporadically.
Fundic glands found in the fundus and also in the body have another two cell types–gastric chief cells and parietal cells (oxyntic cells). Foveolar cells (surface mucous cells) are mucus-producing cells which cover the inside of the stomach, protecting it from the corrosive nature of gastric acid.
Diagram showing gastric pits (13) gastric glands (12) lamina propria (10) epithelium (11) Histology of normal fundic mucosa. Fundic glands are simple, branched tubular glands that extend from the bottom of the gastric pits to the muscularis mucosae; the more distinctive cells are parietal cells. H&E stain. Histology of normal antral mucosa.
Chief cells are part of fundic gland polyps (here shown in high magnification). [11]In gastric tissue, a loss of parietal cells due to chronic inflammation has been shown to affect chief cell differentiation and can induce chief cells to transdifferentiate back into neck cells and can lead to the formation of mucus cell metaplasia known as spasmolytic polypeptide expressing metaplasia (SPEM ...
Histology image: 11303loa – Histology Learning System at Boston University - Digestive System: Alimentary Canal: fundic stomach, gastric glands, lumen" Nosek, Thomas M. "Section 6/6ch4/s6ch4_8". Essentials of Human Physiology. Archived from the original on 2016-03-24. Nosek, Thomas M. "Section 6/6ch4/s6ch4_14". Essentials of Human Physiology.
Histology image: 11103loa – Histology Learning System at Boston University - "Digestive System: Alimentary Canal: esophageal/stomach junction" Slideshow at trinity.edu Archived 2007-09-27 at the Wayback Machine; Slide at pathology.iupui.edu; Slide at ucsd.edu Archived 2019-06-16 at the Wayback Machine; Slide at nhmccd.edu
Foveolar cells in the antrum of stomach. A skewed cross-section of the columns gives a false impression of being stratified epithelium. Foveolar cells line the surface of the stomach and the gastric pits. They constitute a simple columnar epithelium, as they form a single layer of cells and are taller than their width. Other mucus-secreting ...