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The Gleason grading system is used to help evaluate the prognosis of men with prostate cancer using samples from a prostate biopsy. Together with other parameters, it is incorporated into a strategy of prostate cancer staging which predicts prognosis and helps guide therapy. A Gleason score is given to prostate cancer based upon its microscopic ...
A more refined prognosis can be established by consideration of prostate-specific antigen, and grade (i.e. Gleason score in the Gleason grading system). For example, it is common to classify patients into high, intermediate and low-risk groups on the basis of these three factors (TNM stage, PSA and Gleason score).
[note 1] Gleason scores are commonly grouped into "Gleason grade groups", which predict disease prognosis: a Gleason score of 6 is Gleason grade group 1 (best prognosis). A score of 7 (with Gleason scores 4 + 3, or Gleason scores 3 + 4, with the most prominent listed first) can be grade group 2 or 3; it is grade group 2 if the less severe ...
In a separate study of men from the pre prostate cancer screening era managed with watchful waiting (56% over age 70 years), progression to distant metastasis or prostate cancer death was 13.9% and 12.3%, respectively for Gleason score 6 or below, but considerably higher at 18.2 and 22.7%, 30% and 20%, 44.4% and 55.6% for Gleason 3+4, 4+3, and ...
Christina Victoria Grimmie was born to Tina (née Milos) and Albert Grimmie [5] [6] in the Marlton section of Evesham Township, New Jersey, on March 12, 1994. [7] Her mother worked as a receptionist until she was diagnosed with breast cancer; her father worked at Verizon Communications as of 2014. [8]
Herbert John Gleason (February 26, 1916 – June 24, 1987), known as Jackie Gleason, was an American actor, comedian, writer, and composer also known as "The Great One". [ 1 ] [ 2 ] [ 3 ] He developed a style and characters from growing up in Brooklyn , New York, and was known for his brash visual and verbal comedy, exemplified by his city bus ...
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