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Doxepin is a medication belonging to the tricyclic antidepressant (TCA) [10] class of drugs used to treat major depressive disorder, anxiety disorders, chronic hives, and insomnia. [ 10 ] [ 11 ] For hives it is a less preferred alternative to antihistamines . [ 10 ]
Doxepin Dosage for Sleep. Doxepin is typically prescribed for insomnia at a dosage of 3 to 6 milligrams per night. Interestingly, the medication appears to be effective even at a very low dose.
The antidepressant drug doxepin has been associated with a number of different adverse effects, including the following. [1] [2] [3] The incidence of these adverse effects is not totally known as the scarcity of well-designed clinical trials involving doxepin prohibits it.
Remeron (mirtazapine) – an atypical antidepressant, used off-label as a sleep aid; Restoril – a benzodiazepine used to treat insomnia; Risperdal (risperidone) – atypical antipsychotic used to treat schizophrenia, bipolar disorder and irritability associated with autism; Ritalin (methylphenidate) – a stimulant used to treat ADHD
Triazolam is usually used for short-term treatment of acute insomnia and circadian rhythm sleep disorders, including jet lag. It is an ideal benzodiazepine for this use because of its fast onset of action and short half-life. It puts a person to sleep for about 1.5 hours, allowing its user to avoid morning drowsiness.
Furthermore, due to some SNRIs' actions on obesity, patients with major eating disorders such as anorexia nervosa or bulimia should not be prescribed SNRIs. [16] Duloxetine and milnacipran are also contraindicated in patients with uncontrolled narrow-angle glaucoma, as they have been shown to increase incidence of mydriasis .
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