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Dihydrotestosterone (DHT, 5α-dihydrotestosterone, 5α-DHT, androstanolone or stanolone) is an endogenous androgen sex steroid and hormone primarily involved in the growth and repair of the prostate and the penis, as well as the production of sebum and body hair composition.
Before we get into the weeds about DHT blockers, let’s have a quick science lesson on DHT. Short for dihydrotestosterone, DHT is a type of androgen (male sex hormone).
The pathway from progesterone (P4) to DHT is similar to that described above from 17OHP to DHT, but the initial substrate for 5α-reductase is P4 rather than 17OHP. Placental P4 in the male fetus is the feedstock, that is, a starting point, the initial substrate, for the backdoor pathway found operating in multiple non-gonadal tissues.
Anecdotal evidence suggests that DHT (dihydrotestosterone), a very potent androgen, can effectively be used for this purpose with minimal side effects. No scientific studies have confirmed this effect in female anatomy, but research targeting the treatment of micropenis has found that local application of DHT is very effective at stimulating ...
You’ll most likely get local anesthesia to numb your scalp but will remain awake during the surgery. ... This helps fight hair loss because DHT shrinks hair follicles and shortens the hair ...
[6] [7] It decreases circulating DHT levels by up to about 70%. [8] Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%. [9] [10] It can also reduce DHT levels in the prostate by 97 to 99% in men with prostate cancer.