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Costochondritis, also known as chest wall pain syndrome or costosternal syndrome, is a benign inflammation of the upper costochondral (rib to cartilage) and sternocostal (cartilage to sternum) joints. 90% of patients are affected in multiple ribs on a single side, typically at the 2nd to 5th ribs. [1]
Management of chest pain is based on the underlying cause. [1] Initial treatment often includes the medications aspirin and nitroglycerin. [1] [4] The response to treatment does not usually indicate whether the pain is heart-related. [1] When the cause is unclear, the person may be referred for further evaluation. [3]
Costochondritis is a common cause of chest pain, consisting of up to 30% of chest pain complaints in emergency departments. The pain is typically diffused with the upper costochondral or sternocostal junctions most frequently involved, unlike slipping rib syndrome, which involves the lower rib cage.
Tietze syndrome is a rare cause of chest pain. The condition was first described by Tietze in 1921 as a benign, nonsuppurative painful swelling of the superior chondrosternal joints. Costochondritis, a differential diagnosis for Tietze syndrome, characterized by painful, tender, but nonswollen chondrosternal joints, is more common.
Causes: Menstrual cycle related, birth control pills, hormone therapy, psychiatric medication, breast cancer [1] Diagnostic method: Examination, medical imaging [1] Differential diagnosis: Gallstones, thoracic outlet syndrome, costochondritis [2] Treatment: Reassurance after ruling out cancer, medications [2] [1] Medication: Paracetamol, NSAIDs ...
Osteoporosis, including drug- and cancer-related osteoporosis, giant cell tumour of bone and hypercalcaemia of malignancies: Hypercholesterolaemia, cataract, urinary retention, hypocalcaemia, osteonecrosis of the jaw and anaphylaxis. Gemtuzumab ozogamicin: IV: CD33 antibody that induces apoptosis of the tagged cell. Acute myeloid leukaemia
Therapeutic doses may cause a feeling of artificial well-being ("steroid euphoria"). [22] The neuropsychiatric effects are partly mediated by sensitization of the body to the actions of adrenaline. Therapeutically, the bulk of corticosteroid dose is given in the morning to mimic the body's diurnal rhythm; if given at night, the feeling of being ...
Relapsing polychondritis is a systemic disease characterized by repeated episodes of inflammation and in some cases deterioration of cartilage.The disease can be life-threatening if the respiratory tract, heart valves, or blood vessels are affected.