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Tretinoin, also known as all-trans retinoic acid (ATRA), is a medication used for the treatment of acne and acute promyelocytic leukemia. [ 8 ] [ 9 ] [ 10 ] For acne, it is applied to the skin as a cream, gel or ointment. [ 10 ]
Tretinoin. Known by one of its brand names, Retin-A, tretinoin belongs to the synthetic retinoid class of medications. ... Over time, the body absorbs (or “dissolves”) dermal fillers. Side ...
It is a retinoid, meaning it is related to vitamin A, and is found in small quantities naturally in the body. Its isomer , tretinoin , is also an acne drug. The most common adverse effects are dry lips ( cheilitis ), dry and fragile skin ( xeroderma ), dry eyes [ 8 ] and an increased susceptibility to sunburn .
First generation retinoids are produced naturally in the body and interact with their normal biological counterparts, such as retinol binding protein 4 for retinol, retinoid receptors for all-trans-retinoic acid or 9-cis-retinoic acid. [9] 13-cis retinoic acid has an unknown biological pathway but appears to act as a growth factor. [10]
Tretinoin (Retin-A®): Reduces inflammation and prevents clogged pores Adapalene (Differin®): Often less irritating than other retinoids, it’s sometimes prescribed to those with acne and ...
Retinoic acid (simplified nomenclature for all-trans-retinoic acid) is a metabolite of vitamin A 1 (all-trans-retinol) that is required for embryonic development, male fertility, regulation of bone growth and immune function. [2]