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The sharp distinction between apical and baso-lateral domains is maintained by an active mechanism that prevents mixing. The nature of this mechanism is not known, but it clearly depends on the polarity determinants. In the absence of the aPKC complex, the baso-lateral determinants spread into the former apical domain.
Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis , the outermost layer of the skin . Epithelial ( mesothelial ) tissues line the outer surfaces of many internal organs , the corresponding inner surfaces of body cavities , and the inner surfaces of ...
A brush border (striated border or brush border membrane) is the microvillus-covered surface of simple cuboidal and simple columnar epithelium found in different parts of the body. Microvilli are approximately 100 nanometers in diameter and their length varies from approximately 100 to 2,000 nanometers.
The brush border on the apical surface of the epithelial cells is covered with glycocalyx, which is composed of oligosaccharides attached to membrane glycoproteins and glycolipids. [7] TEM image of a thin section cut through an epithelial cell showing the luminal surface (apical end) of the cell packed with microvilli that make up the absorbing ...
The shape of the simple columnar epithelium cells are tall and narrow giving a column like appearance. the apical surfaces of the tissue face the lumen of organs while the basal side faces the basement membrane. [1] The nuclei are located closer along the basal side of the cell. [1]
Transitional epithelium animation, highlighting the epithelial layer, then underlying connective tissue. Contrast the messy appearance of the epithelial surface to other epithelial tissues. Transitional epithelium is a type of stratified epithelium. [1]
Here, actin polymerization in the direction of migration allows cells to extend the leading edge of the cell and to attach to the surface. [5] At the rear of the cell, adhesions are disassembled and bundles of actin microfilaments , called stress fibers , contract and pull the trailing edge forward to keep up with the rest of the cell.
The terminal web is a filamentous structure found at the apical surface of epithelial cells that possess microvilli.It is composed primarily of actin filaments stabilized by spectrin, which also anchors the terminal web to the apical cell membrane.