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Clear cell sarcoma is a sub-type of a rare form of cancer called a sarcoma. [1] It is known to occur mainly in the soft tissues and dermis.Rare forms were thought to occur in the gastrointestinal tract before they were discovered to be different and redesignated as gastrointestinal neuroectodermal tumors.
In addition to these variables, expression levels and copy number variations of a number of relevant genes may be used to support assessment of melanoma prognosis. [115] [116] Stage IV melanoma, in which it has metastasized, is the most deadly skin malignancy: five-year survival is 22.5%. [133]
In comparison, the mortality rate of melanoma is 15–20% and it causes 6500 deaths per year. [67]: 29, 31 Even though it is much less common, malignant melanoma is responsible for 75% of all skin cancer-related deaths. [68] The survival rate for people with melanoma depends upon when they start treatment.
The prognosis varies dramatically, depending on the type and stage at the time of treatment. However, the most common epitheliomas are very easily treated and rarely result in death. [ 2 ] The condition did, however, take the life of Scottish golfer Willie Dunn, Sr. in 1878 at a time when the ailment was likely not fully understood.
In the United States there has been an increase in the 5-year relative survival rate between people diagnosed with cancer in 1975-1977 (48.9%) and people diagnosed with cancer in 2007-2013 (69.2%); these figures coincide with a 20% decrease in cancer mortality from 1950 to 2014. [8]
Epithelioid sarcoma is a slow-growing and relatively painless tumor, often resulting in a lengthy period of time between presentation and diagnosis. [8] Due to the difficulty of discerning this cancer as different from more common cancers, such as cancers of the skin (squamous cell carcinoma or basal cell carcinoma), it is often misdiagnosed, mistaken as a persistent wart or cyst.
Sclerosing epithelioid fibrosarcoma (SEF) is a very rare malignant tumor of soft tissues that on microscopic examination consists of small round or ovoid neoplastic epithelioid fibroblast-like cells, i.e. cells that have features resembling both epithelioid cells and fibroblasts. [1]
A sarcoma is a malignant tumor, a type of cancer that arises from cells of mesenchymal (connective tissue) origin. [1] [2] Connective tissue is a broad term that includes bone, cartilage, muscle, fat, vascular, or other structural tissues, and sarcomas can arise in any of these types of tissues.
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