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AFP-L3% is the standard for quantifying the L3 isoform of AFP in serum of high risk chronic liver disease (CLD) patients. Studies have shown that AFP-L3% test results of more than 10% can be indicative of early HCC [citation needed] or early nonseminomatous germ cell tumor. [1] Early testimonials from hepatologists indicate that there is a ...
AFP is normally elevated in infants, and because teratoma is the single most common kind of tumor in infants, several studies have provided reference ranges for AFP in normal infants. [ 5 ] [ 6 ] [ 7 ] Perhaps the most useful is this equation: log Y = 7.397 - 2.622.log (X + 10), where X = age in days and Y = AFP level in nanograms per ...
Alpha-fetoprotein (AFP, α-fetoprotein; also sometimes called alpha-1-fetoprotein, alpha-fetoglobulin, or alpha fetal protein) is a protein [5] [6] that in humans is encoded by the AFP gene. [ 7 ] [ 8 ] The AFP gene is located on the q arm of chromosome 4 (4q13.3). [ 9 ]
A low AFP in a pregnant person can indicate Down syndrome. There are 3 forms of AFP: L1, L2, and L3. L1 is the form associated most commonly with liver disease and L3 is most commonly associated with malignant tumors. AFP-L3 can be used to detect hepatocellular carcinoma early on when compared to overall AFP levels.
Moreover, it has been demonstrated that a combined analysis of DCP and Alpha-fetoprotein (AFP) can lead to a better prediction in early stages of HCC. [7] Despite many years of use in Japan, only did a 2003 American study reevaluate its use in an American patient series. It also identified HCC at an earlier stage. [4]
Alpha fetoprotein (AFP) germ cell tumor, hepatocellular carcinoma [9] CA15-3: breast cancer [10] CA27.29: breast cancer [11] CA19-9: Mainly pancreatic cancer, but also colorectal cancer and other types of gastrointestinal cancer. [12] CA-125
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