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In genetics, association mapping, also known as "linkage disequilibrium mapping", is a method of mapping quantitative trait loci (QTLs) that takes advantage of historic linkage disequilibrium to link phenotypes (observable characteristics) to genotypes (the genetic constitution of organisms), uncovering genetic associations. [1] [2]
Standard gene mapping software packages can be used, although it is often faster to use custom code such as QTL Reaper or the web-based eQTL mapping system GeneNetwork. GeneNetwork hosts many large eQTL mapping data sets and provide access to fast algorithms to map single loci and epistatic interactions. As is true in all QTL mapping studies ...
The choice of marker covariates has not been solved, however. Not surprisingly, the appropriate markers are those closest to the true QTLs, and so if one could find these, the QTL mapping problem would be complete anyway. Inclusive composite interval mapping (ICIM) has also been proposed as a potential method for QTL mapping. [22]
Quantitative trait loci mapping or QTL mapping is the process of identifying genomic regions that potentially contain genes responsible for important economic, health or environmental characters. Mapping QTLs is an important activity that plant breeders and geneticists routinely use to associate potential causal genes with phenotypes of interest.
Its function is: (1) implementation of mapping methods including single marker analysis, interval mapping, ICIM for additive and dominance, ICIM for digenic epistasis, selective phenotyping, etc.; (2) QTL linkage analysis more than twenty mapping populations derived from bi-parental cross, including backcross, double haploid, recombinant inbred ...
Splicing quantitative trait loci (abbreviated sQTLs or splicing QTLs) are quantitative trait loci that regulate alternative splicing of pre-mRNA.They can be detected using RNA-seq data.
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It is recommended to name the SVG file “QTL mapping using inbred strains.svg”—then the template Vector version available (or Vva) does not need the new image name parameter. File history Click on a date/time to view the file as it appeared at that time.