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Primary central nervous system lymphoma (PCNSL), also termed primary diffuse large B-cell lymphoma of the central nervous system (DLBCL-CNS), [2] is a primary intracranial tumor appearing mostly in patients with severe immunodeficiency (typically patients with AIDS). It is a subtype and one of the most aggressive of the diffuse large B-cell ...
CNS metastasis is the spread and proliferation of cancer cells from their original tumour to form secondary tumours in portions of the central nervous system. [ 1 ] The process of tumour cells invading distant tissue is complex and obscure, but modern technology has permitted an enhanced detection of metastasis .
Cellular deconvolution algorithms have been applied to a variety of samples collected from saliva, [5] buccal, [5] cervical, [5] PBMC, [6] brain, [2] kidney, [1] and pancreatic cells, [1] and many studies have shown that estimating and incorporating the proportions of cell types into various analyses improves the interpretability of high ...
A central nervous system tumor (CNS tumor) is an abnormal growth of cells from the tissues of the brain or spinal cord. [1] CNS tumor is a generic term encompassing over 120 distinct tumor types. [2] Common symptoms of CNS tumors include vomiting, headache, changes in vision, nausea, and seizures. [3]
Neuroimaging is the use of quantitative (computational) techniques to study the structure and function of the central nervous system, developed as an objective way of scientifically studying the healthy human brain in a non-invasive manner. Increasingly it is also being used for quantitative research studies of brain disease and psychiatric ...
Neurogenetics is a field that is rapidly expanding and growing. The current areas of research are very diverse in their focuses. One area deals with molecular processes and the function of certain proteins, often in conjunction with cell signaling and neurotransmitter release, cell development and repair, or neuronal plasticity.
Certain anatomical sites exhibit a heightened risk for CNS relapse due to their proximity to the central nervous system or unique immune properties. The most widely recognized sites are the kidney and adrenal glands, which have already been incorporated into the CNS-IPI score. Breast and testicular involvement show growing significance as well. [3]
1928: One of the earliest accounts of being able to record from the nervous system was by Edgar Adrian in his 1928 publication "The Basis of Sensation". In this, he describes his recordings of electrical discharges in single nerve fibers using a Lippmann electrometer. He won the Nobel Prize in 1932 for his work revealing the function of neurons.