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Drug orders are generated based on patient parameters such as age, weight, renal and hepatic impairment, thereby reducing lists of candidate drugs to a minimum. The database is expected to affect the number of adverse drug reactions and side effects at facilities that have adopted the electronic order entry systems.
Examples of approved drugs that act as renal tubular transport inhibitors include: Probenecid : This is an inhibitor of the organic anion transport system, particularly OAT1 and OAT3. [ 2 ] [ 1 ] It is used clinically to increase the systemic concentrations of certain drugs by reducing their renal excretion.
The fifth version in 1957 saw its name change to The British National Formulary. [ 4 ] [ 5 ] A new-look version, under the auspices of Owen Wade , was released in 1981. [ 2 ] [ 6 ] A study in Northern Ireland, looking at prescribing in 1965, reported that the BNF was likely able to serve the requirements of prescribers in general practice ...
Martindale: The Complete Drug Reference is a reference book published by Pharmaceutical Press listing some 6,000 drugs and medicines used throughout the world, including details of over 125,000 proprietary preparations. It also includes almost 700 disease treatment reviews.
Acute kidney injury (AKI), previously called acute renal failure (ARF), [12] [13] is a rapidly progressive loss of renal function, [14] generally characterized by oliguria (decreased urine production, quantified as less than 400 mL per day in adults, [15] less than 0.5 mL/kg/h in children or less than 1 mL/kg/h in infants); and fluid and ...
This greatly expanded and improved version of the database included 1344 approved small molecule drugs and 123 biotech drugs as well as 3037 unique drug targets. Version 2.0 also included, for the first time, withdrawn drugs and illicit drugs , extensive food-drug and drug-drug interactions as well as ADMET (absorption, distribution, metabolism ...