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Croup (/ k r uː p / KROOP), also known as croupy cough, is a type of respiratory infection that is usually caused by a virus. [2] The infection leads to swelling inside the trachea, which interferes with normal breathing and produces the classic symptoms of "barking/brassy" cough, inspiratory stridor and a hoarse voice. [2]
Prednisolone has a relatively short half-life, ranging 2–4 hours. It also has a large therapeutic window, considering the dosage required to produce a therapeutic effect is a few times higher than what the body naturally produces. [14] Prednisolone is 70–90% plasma protein bound, it binds to proteins such as albumin. [14]
Dexamethasone is commonly given as a treatment for croup in children. [25] A single dose can reduce the swelling of the airway to improve breathing and reduce discomfort. [25] Dexamethasone is sometimes injected into the heel when treating plantar fasciitis or heel pain, sometimes in conjunction with triamcinolone acetonide. There is no ...
Methylprednisolone dosage and administration for these diseases is highly variable due to varied pathophysiology between the diseases and within patients diagnosed with a given disease. [ 17 ] [ 18 ] In Lupus Nephritis, a common manifestation of SLE, patients are often prescribed methylprednisolone concomitantly with immunosuppressants.
Perioperative stress dose of steroids to mitigate this rare but potentially fatal complications of perioperative use of steroid such as full-blown adrenal crisis in the perioperative period due to the secondary adrenal insufficiency. Various exogenous steroid preparations are used for a wide range of indications. [1]
"Organizing" refers to unresolved pneumonia (in which the alveolar exudate persists and eventually undergoes fibrosis) in which fibrous tissue forms in the alveoli.The phase of resolution and/or remodeling following bacterial infections is commonly referred to as organizing pneumonia, both clinically and pathologically.
Chronic obstructive pulmonary disease (COPD) is a type of progressive lung disease characterized by chronic respiratory symptoms and airflow limitation. [8] GOLD 2024 defined COPD as a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea or shortness of breath, cough, sputum production or exacerbations) due to abnormalities of the airways (bronchitis ...
Prednisolone acetate is acutely toxic with an LD50 of >240 mg/kg for a rat and 3500 mg/kg for a mouse. Effects may present delayed. Target organs include adrenal cortex, bones, and eyes. It is also a known teratogen. [3] Class B PPE should be worn when working with this chemical. Any contact with this chemical should be taken seriously and the ...