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GSVA [153] gene set variation analysis for microarray and RNA-Seq data. Heat*Seq an interactive web tool for high-throughput sequencing experiment comparison with public data. Ingenuity Systems (commercial) iReport & IPA; PathwaySeq [154] Pathway analysis for RNA-Seq data using a score-based approach. petal Co-expression network modelling in R.
PhiX174 is able to undergo genetic recombination. Based on recombination frequencies obtained in genetic crosses, a genetic map was constructed. [24] Recombination in phi X174 is associated with high negative interference, i.e a positive correlation (negative interference) of recombinational events (see wikipedia crossover interference). [24]
There are two distinctive mapping approaches used in the field of genome mapping: genetic maps (also known as linkage maps) [7] and physical maps. [3] While both maps are a collection of genetic markers and gene loci, [8] genetic maps' distances are based on the genetic linkage information, while physical maps use actual physical distances usually measured in number of base pairs.
Crossover in evolutionary algorithms and evolutionary computation, also called recombination, is a genetic operator used to combine the genetic information of two parents to generate new offspring. It is one way to stochastically generate new solutions from an existing population, and is analogous to the crossover that happens during sexual ...
Where d is the distance in map units, the Morgan Mapping Function states that the recombination frequency r can be expressed as =.This assumes that one crossover occurs, at most, in an interval between two loci, and that the probability of the occurrence of this crossover is proportional to the map length of the interval.
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In recent years, there has been an advent of new kinds of assemblers capable of integrating linkage data from multiple types of linkage maps. ALLMAPS is the first of such programs and is capable of combining data from genetic maps, created using SNPs or recombination data, with physical maps such as optical or synteny maps. [7]
Physical map is a technique used in molecular biology to find the order and physical distance between DNA base pairs by DNA markers. [1] It is one of the gene mapping techniques which can determine the sequence of DNA base pairs with high accuracy. Genetic mapping, another approach of gene mapping, can provide markers needed for the physical ...