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  2. Gastrointestinal tract - Wikipedia

    en.wikipedia.org/wiki/Gastrointestinal_tract

    The human gastrointestinal tract consists of the esophagus, stomach, and intestines, and is divided into the upper and lower gastrointestinal tracts. [3] The GI tract includes all structures between the mouth and the anus , [ 4 ] forming a continuous passageway that includes the main organs of digestion, namely, the stomach , small intestine ...

  3. Morphine - Wikipedia

    en.wikipedia.org/wiki/Morphine

    The euphoria, comprehensive alleviation of distress and therefore all aspects of suffering, promotion of sociability and empathy, "body high", and anxiolysis provided by narcotic drugs including opioids can cause the use of high doses in the absence of pain for a protracted period, which can impart a craving for the drug in the user. [156]

  4. Oxycodone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone

    [45] [46] Less common side effects (experienced by less than 5% of patients) include loss of appetite, nervousness, abdominal pain, diarrhea, urinary retention, dyspnea, and hiccups. [47] Most side effects generally become less intense over time, although issues related to constipation are likely to continue for the duration of use. [48]

  5. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    This requires them to increase their drug dosage to maintain the benefit, and that in turn also increases the unwanted side effects. [78] Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. [101] All of the opioids can cause side effects. [70]

  6. Analgesic - Wikipedia

    en.wikipedia.org/wiki/Analgesic

    An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management.Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and ...

  7. Tramadol - Wikipedia

    en.wikipedia.org/wiki/Tramadol

    Tramadol, sold under the brand name Ultram among others, [1] is an opioid pain medication and a serotonin–norepinephrine reuptake inhibitor (SNRI) used to treat moderately severe pain. [12] [16] When taken by mouth in an immediate-release formulation, the onset of pain relief usually begins within an hour. [12] It is also available by ...

  8. Hydromorphone - Wikipedia

    en.wikipedia.org/wiki/Hydromorphone

    A 2016 Cochrane review (updated in 2021) found little difference in benefit between hydromorphone and other opioids for cancer pain. [10] Common side effects include dizziness, sleepiness, nausea, itchiness, and constipation. [7] Serious side effects may include abuse, low blood pressure, seizures, respiratory depression, and serotonin syndrome ...

  9. Oxymorphone - Wikipedia

    en.wikipedia.org/wiki/Oxymorphone

    Oxymorphone (sold under the brand names Numorphan and Opana among others) is a highly potent opioid analgesic indicated for treatment of severe pain. Pain relief after injection begins after about 5–10 minutes, after oral administration it begins after about 30 minutes, and lasts about 3–4 hours for immediate-release tablets and 12 hours for extended-release tablets. [6]