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MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like episodes) is one of the family of mitochondrial diseases, which also include MIDD (maternally inherited diabetes and deafness), MERRF syndrome, and Leber's hereditary optic neuropathy. It was first characterized under this name in 1984. [2]
One Piece is an anime television series based on the manga series of the same name. As of 2025, it has more than 1,100 episodes. As of 2025, it has more than 1,100 episodes. Series overview
Sonlicromanol was principally developed as drug to release symptoms for patients with mitochondrial diseases like Leigh's disease, MELAS (Mitochondrial, Encephalomyopathy, Lactic acidosis, and Stroke-like episodes) spectrum disorders, and LHON (Leber's Hereditary Optic Neuropathy).
The One Piece anime series, based on the manga of same name, has spawned thirteen television specials that aired on Fuji TV. Of these specials, the first four, as well as the sixth, eighth, tenth and eleventh are original stories created by the anime staff, while the fifth, seventh, ninth, twelfth and thirteenth specials are alternate re ...
Ranking every single story arc in One Piece from worst to best, taking into account both the anime and manga.
Like the rest of the series, this season follows the member of the Four Emperors Monkey D. Luffy's adventures with his Straw Hat Pirates. The season adapts material from the "Egghead" arc, from the rest of the 105th volume onwards of the manga series of the same name by Eiichiro Oda .
According to the World Stroke Association, one in four adults over the age of 25 will have a stroke during their lifetime, and there are about 12.2 million new strokes diagnosed each year.
Mitochondrial myopathies are types of myopathies associated with mitochondrial disease. [1] Adenosine triphosphate (), the chemical used to provide energy for the cell, cannot be produced sufficiently by oxidative phosphorylation when the mitochondrion is either damaged or missing necessary enzymes or transport proteins.