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The majority of cases are caused by malignant tumors within the mediastinum, most commonly lung cancer and non-Hodgkin's lymphoma, directly compressing or invading the SVC wall. Non-malignant causes are increasing in prevalence due to expanding use of intravascular devices (such as permanent central venous catheters and leads for pacemakers and ...
A lung illustration depicting a pulmonary embolism as a thrombus (blood clot) that has travelled from another region of the body, causes occlusion of the pulmonary bronchial artery, leading to arterial thrombosis of the superior and inferior lobes in the left lung: Specialty: Hematology, cardiology, pulmonology, Emergency medicine: Symptoms
Cancer can grow in and around veins, causing venous stasis, and can also stimulate increased levels of tissue factor. [83] Cancers of the blood, lung, pancreas, brain, stomach, and bowel are associated with high VTE risk. [84] Solid tumors such as adenocarcinomas can contribute to both VTE and disseminated intravascular coagulation.
Clubbing is associated with lung cancer, lung infections, interstitial lung disease, cystic fibrosis, or cardiovascular disease. [5] Clubbing may also run in families, [5] and occur unassociated with other medical problems. [6] [7] Clubbing has been recognized as a sign of disease since the time of Hippocrates. [5]
[2] [7] [8] Ischemic stroke is typically caused by blockage of a blood vessel, though there are also less common causes. [13] [14] [15] Hemorrhagic stroke is caused by either bleeding directly into the brain or into the space between the brain's membranes. [13] [16] Bleeding may occur due to a ruptured brain aneurysm. [13]
An embolism can cause partial or total blockage of blood flow in the affected vessel. [2] Such a blockage (vascular occlusion) may affect a part of the body distant from the origin of the embolus. An embolism in which the embolus is a piece of thrombus is called a thromboembolism. An embolism is usually a pathological event, caused by illness ...
An aneurysm is an outward bulging, likened to a bubble or balloon, caused by a localized, abnormal, weak spot on a blood vessel wall. [1] Aneurysms may be a result of a hereditary condition or an acquired disease. Aneurysms can also be a nidus (starting point) for clot formation and embolization.
A mediastinal tumor is a tumor in the mediastinum, the cavity that separates the lungs from the rest of the chest. It contains the heart , esophagus , trachea , thymus , and aorta . The most common mediastinal masses are thymoma (20% of mediastinal tumors), usually found in the anterior mediastinum, followed by neurogenic Timor (15–20% ...