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The distinguishing characteristics of POIS are: the rapid onset of symptoms after orgasm; the presence of an overwhelming systemic reaction. [1]POIS symptoms, which are called a "POIS attack", [1] can include some combination of the following: cognitive dysfunction, aphasia, severe muscle pain throughout the body, severe fatigue, weakness, and flu-like or allergy-like symptoms, [4] such as ...
Symptoms start at around 6 hours after the last drink. [2] Peak incidence of seizures occurs at 24 to 36 hours [5] and peak incidence of delirium tremens is at 48 to 72 hours. [6] Alcohol withdrawal may occur in those who are alcohol dependent. [1] This may occur following a planned or unplanned decrease in alcohol intake. [1]
Insufficient quality or quantity of night time sleep [5] Obstructive sleep apnea [6] Misalignments of the body's circadian pacemaker with the environment (e.g., jet lag, shift work, or other circadian rhythm sleep disorders) [7] Another underlying sleep disorder, such as narcolepsy, sleep apnea, [8] idiopathic hypersomnia, or restless legs syndrome
The goal of nocturnal penile tumescence testing is to determine whether one can experience an erection while sleeping after reporting that they are unable to experience an erection while awake. On average, one has 3–5 episodes of NPT each night, and each episode lasts 30–60 minutes, although the duration is reduced with advanced age. [16]
[41] [42] [43] The advantage actigraphy shows over polysomnography is that it is possible to record for 24-hours a day for weeks. [41] Furthermore, unlike the polysomnography, it is less expensive and non-invasive. [41] An actigraphy over several days can show longer sleep periods, which are characteristic for idiopathic hypersomnia. [44]
Studies on rodents show that the response to neuronal injury due to acute sleep deprivation is adaptative before three hours of sleep loss per night and becomes maladaptative, and apoptosis occurs after. [35] Studies in mice show neuronal death (in the hippocampus, locus coeruleus, and medial PFC) occurs after two days of REM sleep deprivation.
Occasional noncircadian days may occur (i.e., sleep is "skipped" for an entire day and night plus some portion of the following day), followed by a sleep period lasting 12 to 18 hours. The symptoms do not meet the criteria for any other sleep disorder causing inability to initiate sleep or excessive sleepiness.
[24] A feature that hypnagogia shares with other stages of sleep is amnesia . But this is a selective forgetfulness, affecting the hippocampal memory system, which is responsible for episodic or autobiographical memory , rather than the neocortical memory system, responsible for semantic memory . [ 6 ]