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Pseudoephedrine, sold under the brand name Sudafed among others, is a sympathomimetic medication which is used as a decongestant to treat nasal congestion. [1] [13] [2] It has also been used off-label for certain other indications, like treatment of low blood pressure.
ATC code C09 Agents acting on the renin–angiotensin system is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
The Biopharmaceutics Classification System (BCS) is a system to differentiate drugs on the basis of their solubility and permeability. [1] This system restricts the prediction using the parameters solubility and intestinal permeability. The solubility classification is based on a United States Pharmacopoeia (USP) aperture.
The ATC system also includes defined daily doses (DDDs) for many drugs. This is a measurement of drug consumption based on the usual daily dose for a given drug. According to the definition, "[t]he DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults." [15]
Pseudoephedrine is a drug used alone or in combination with other medicines to treat a blocked nose due to cold, flu or allergy. Makers of pseudoephedrine-containing drugs include Reckitt ...
A drug class is a group of medications and other compounds that share similar chemical structures, act through the same mechanism of action (i.e., binding to the same biological target), have similar modes of action, and/or are used to treat similar diseases.
Ramipril, a prodrug or precursor drug, is converted to the active metabolite ramiprilat by carboxylesterase 1. [ 17 ] [ 18 ] Ramiprilat is mostly excreted by the kidneys . Its half-life is variable (3–16 hours), and is prolonged by heart and liver failure , as well as kidney failure .
Sudafed is a brand manufactured by McNeil Laboratories. [ citation needed ] The original formulation contains the active ingredient pseudoephedrine , but formulations without pseudoephedrine are also being sold under the brand.