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Aliskiren (brand names Tekturna and Rasilez) is the first in a class of drugs called direct renin inhibitors. It is used for essential (primary) hypertension . [ 2 ] While used for high blood pressure, other better studied medications are typically recommended due to concerns of higher side effects and less evidence of benefit.
Aliskiren, the third-generation renin inhibitor. Aliskiren, an orally active non-peptide renin inhibitor, was the first drug in its class on the market. It is used to treat hypertension as monotherapy or in combination with other antihypertensive agents. [7] [39] The key to the discovery of aliskiren was crystallography and molecular modeling ...
[1] [2] It contains aliskiren, a renin inhibitor; amlodipine, as the besylate, a calcium channel blocker; and hydrochlorothiazide, a thiazide diuretic. [1] It is taken by mouth . [ 1 ]
Considerations include factors such as age, race, and other medical conditions. [47] In the United States, JNC8 (2014) recommends any drug from one of the four following classes to be a good choice as either initial therapy or as an add-on treatment: thiazide -type diuretics, calcium channel blockers , ACEis, or ARBs.
Transportation Secretary Sean Duffy in the James Brady Press Briefing Room at the White House, Thursday, Jan. 30, 2025, in Washington. (AP Photo/Jacquelyn Martin) (ASSOCIATED PRESS)
The president's attempt to ban trans women from preferred sports teams on Wednesday won't have wide-ranging implications, legal experts say. Transgender minors are fighting back against the Trump ...
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Aliskiren/hydrochlorothiazide, sold under the brand name Tekturna HCT among others, is a fixed-dose combination medication for the treatment of hypertension ...