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  2. Polysulfated glycosaminoglycan - Wikipedia

    en.wikipedia.org/wiki/Polysulfated_glycosaminoglycan

    [3] [4] In vitro studies have shown it to inhibit the enzymes that degrade cartilage and bone, as well as suppress inflammation and stimulate the synthesis of replacement cartilage. While it can cause an increased risk of bleeding, it is relatively safe and has a high LD50 .

  3. Grapiprant - Wikipedia

    en.wikipedia.org/wiki/Grapiprant

    The approximate calculation for canine efficacy dose is between the range of 1.3 and 1.7 mg/kg, in conjunction with a methylcellulose suspending agent. Based on the calculations from the comparisons of binding affinity of grapiprant to the EP4 receptors of dogs, rats, and humans, the study of plasma and serum protein binding determinations, the ...

  4. Rabacfosadine - Wikipedia

    en.wikipedia.org/wiki/Rabacfosadine

    Rabacfosadine, sold under the brand name Tanovea, is a guanine nucleotide analog used for the treatment of lymphoma in dogs. [1] It was developed by Gilead Sciences as GS-9219. [2] The active form of rabacfosadine is a chain-terminating inhibitor of the major deoxyribonucleic acid (DNA) polymerases.

  5. Medetomidine - Wikipedia

    en.wikipedia.org/wiki/Medetomidine

    Medetomidine is a racemic mixture of two optical or stereoisomers, levomedetomidine and dexmedetomidine. [4] The latter causes the alpha 2- adrenergic agonist effects. [5] It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid that can be administered as an intravenous drug solution with sterile water.

  6. Atipamezole - Wikipedia

    en.wikipedia.org/wiki/Atipamezole

    Atipamezole is a veterinary drug whose prime purpose is to reverse the effects of the sedative dexmedetomidine (as well as its racemic mixture, medetomidine). [note 1] [9] [10] It can also be used to reverse the related sedative xylazine. [11]

  7. Pimobendan - Wikipedia

    en.wikipedia.org/wiki/Pimobendan

    The reaction of this with hydrazine gives 5-methyl-6-[3-nitro-4-(4-methoxy-benzoylamino)-phenyl]-3-oxo-4,5-dihydro-2H-pyridazine [74149-73-8]. Catalytic hydrogenation reduces the nitro group giving [74149-74-9] ( 4 ). cyclization of the resulting ortho amino amide by means of a strong acid leads to the formation of the corresponding benzimidazole.

  8. Every (explosive-sniffing) dog has their (graduation) day - AOL

    www.aol.com/every-explosive-sniffing-dog...

    Dogs trained in explosives and accelerant detection, along with their handlers, head into a graduation ceremony at the Bureau of Alcohol, Tobacco, Firearms and Explosives National Canine Division ...

  9. Maropitant - Wikipedia

    en.wikipedia.org/wiki/Maropitant

    Maropitant (INN; [3] brand name: Cerenia, used as maropitant citrate , is a neurokinin-1 (NK 1) receptor antagonist developed by Zoetis specifically for the treatment of motion sickness and vomiting in dogs. It was approved by the FDA in 2007, for use in dogs [4] [5] and in 2012, for cats. [6]

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    free 1 4 moa chart for dogs images black and white 3 grade graduation cap