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The modified Rankin Scale (mRS) is a commonly used scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability. It has become the most widely used clinical outcome measure for stroke clinical trials. [1] [2]
Latest stroke prevention guidelines highlight the importance of lifestyle interventions for cardiovascular health and managing conditions such as type 2 diabetes and high blood pressure.
The “2024 Guideline for the Primary Prevention of Stroke,” published in the journal Stroke and replacing the 2014 version, focuses on identifying and managing risk factors—particularly for ...
The National Institutes of Health Stroke Scale, or NIH Stroke Scale (NIHSS), is a tool used by healthcare providers to objectively quantify the impairment caused by a stroke and aid planning post-acute care disposition, though was intended to assess differences in interventions in clinical trials. The NIHSS was designed for the National ...
The scale is regarded as reliable, although its use in clinical trials in stroke medicine is inconsistent. [4] It has however, been used extensively to monitor functional changes in individuals receiving in-patient rehabilitation, mainly in predicting the functional outcomes related to stroke.
For example, a person aged 60 (1 point) with normal blood pressure (0 point) and without diabetes (0 point) who experienced a TIA lasting 10 minutes (1 point) with a speech disturbance but no weakness on one side of the body (1 point) would score a total of 3 points.
Remote ischemic conditioning (RIC) is an experimental medical procedure that aims to reduce the severity of ischaemic injury to an organ such as the heart or the brain, most commonly in the situation of a heart attack or a stroke, or during procedures such as heart surgery when the heart may temporary suffer ischaemia during the operation, by triggering the body's natural protection against ...
Even a single stroke risk factor confers excess risk of stroke and mortality, with a positive net clinical benefit for stroke prevention with oral anticoagulation, when compared to no treatment or aspirin. [25] As mentioned above, thromboembolic event rates differ according to various guideline treatment thresholds and methodological approaches ...