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The modified Rankin Scale (mRS) is a commonly used scale for measuring the degree of disability or dependence in the daily activities of people who have suffered a stroke or other causes of neurological disability. It has become the most widely used clinical outcome measure for stroke clinical trials. [1] [2]
A cerebroprotectant (formerly known as a neuroprotectant) is a drug that is intended to protect the brain after the onset of acute ischemic stroke. [1] As stroke is the second largest cause of death worldwide and a leading cause of adult disability, over 150 drugs have been tested in clinical trials to provide cerebroprotection.
It found that the conditioning reduced the incidence of recurrent stroke from 23.3% to 5% at 90 days, and from 26.7% to 7.9% at 300 days; it also improved the rate of recovery (measured with the modified Rankin scale) and cerebral perfusion. The second trial examined the effect of 180 days of RIC on symptomatic ICAS in Chinese people aged 80 ...
More than 795,000 people in the U.S. have a stroke each year, which is a leading cause of serious long-term disability. Many of the leading risk factors for stroke are modifiable, making ...
The Glasgow Outcome Scale (GOS) is an ordinal scale used to assess functional outcomes of patients following brain injury. It considers several factors, including a patient's level of consciousness, ability to carry out activities of daily living (ADLs), and ability to return to work or school.
The National Institutes of Health Stroke Scale, or NIH Stroke Scale (NIHSS), is a tool used by healthcare providers to objectively quantify the impairment caused by a stroke and aid planning post-acute care disposition, though was intended to assess differences in interventions in clinical trials. The NIHSS was designed for the National ...
ascertain function after stroke (or cancer) The Functional Independence Measure ( FIM ) is an assessment tool that aims to evaluate the functional status of patients throughout the rehabilitation process following a stroke , traumatic brain injury , spinal cord injury or cancer . [ 1 ]
For example, a person aged 60 (1 point) with normal blood pressure (0 point) and without diabetes (0 point) who experienced a TIA lasting 10 minutes (1 point) with a speech disturbance but no weakness on one side of the body (1 point) would score a total of 3 points.