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The epiphyseal plate, epiphysial plate, physis, or growth plate is a hyaline cartilage plate in the metaphysis at each end of a long bone.It is the part of a long bone where new bone growth takes place; that is, the whole bone is alive, with maintenance remodeling throughout its existing bone tissue, but the growth plate is the place where the long bone grows longer (adds length).
It contains the growth plate, the part of the bone that grows during childhood, and as it grows it ossifies near the diaphysis and the epiphyses. The metaphysis contains a diverse population of cells including mesenchymal stem cells , which give rise to bone and fat cells, as well as hematopoietic stem cells which give rise to a variety of ...
Linear growth takes place in the epiphyseal growth plates (EGP) of long bones. [23] In the growth plate, chondrocytes proliferate, hypertrophy and secrete cartilage extracellular matrix. New cartilage is subsequently remodeled into bone tissue, causing bones to grow longer. [24]
These bones are located just beyond the wrist and serve as a link to the phalanges, or finger bones, at the end of the limbs. In the lower body, the femur is a prominent bone positioned between the hip and knee. As the longest bone in the human body, it plays a pivotal role in forming the upper part of the knee joint.
These include fibrocartilaginous and hyaline joints, which usually occur at the midline. Some examples of secondary cartilaginous joints in human anatomy would be the manubriosternal joint (between the manubrium and the body of the sternum), intervertebral discs, and the pubic symphysis. Articulating bones at a symphysis are covered with ...
Epiphyseal growth plate: This transverse layer lies between the epiphysis and diaphysis. It’s composed of highly active chondrocytes and responsible for longitudinal bone growth. Consequently, the bone elongates at this growth plate until closure occurs at skeletal maturity.
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This can point to a couple different changes in development: either this growth plate loss in humans is also accompanied by a developmental shift in the timing of pisiform formation, or it is the primary center that fails to form in humans and as a result our pisiform is homologous to the epiphysis of other mammalian pisiforms. [2]