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(A) Zebrafish notochord. (B) Ascidian notochord. (C) Lancelet notochord. Notochord is positioned just ventral to the neural tube and dorsal to the gut, flanked by myotome. (D) Notochord homolog in annelid. Cross-section showing the position of the proposed axochord to the ventral mesentery, blood vessel, and nerve chord.
The notochord will form the nucleus pulposus of intervertebral discs. There is some discussion as to whether these cells contributed from the notochord are replaced by others from the adjacent mesoderm. It gives rise to the notochordal process, which later becomes the notochord.
The mesoderm is one of the three germinal layers that appears in the third week of embryonic development. It is formed through a process called gastrulation. There are four important components, which are the axial, paraxial, intermediate, and lateral plate mesoderms. The axial mesoderm gives rise to the notochord.
Both Shh and HNF-3b transcripts are found in the notochord and the floor plate rostral to the node, and they are completely absent in the lateral and caudal neural plate and the primitive streak. In the node proper, the chordin expression pattern is very similar to that of HNF-3b, but more rostrally, chordin is no longer expressed in the floor ...
The notochord extends from the base of the head to the tail; with it extend thick bands of paraxial mesoderm. [ 3 ] As the primitive streak continues to regress, somites form from the paraxial mesoderm by "budding off" rostrally.
These mesodermal cells that migrate along the dorsal midline give rise to a structure called the notochord. Ectodermal cells overlying the notochord develop into the neural plate in response to a diffusible signal produced by the notochord. The remainder of the ectoderm gives rise to the epidermis (skin).
Mesodermal cells migrate along the dorsal midline to give rise to the notochord that develops into the vertebral column. Neuroectoderm overlying the notochord develops into the neural plate in response to a diffusible signal produced by the notochord. The remainder of the ectoderm gives rise to the epidermis.
The notochord extends from the base of the head to the tail; with it extend thick bands of paraxial mesoderm. [ 1 ] As the primitive streak continues to regress, somites form from the paraxial mesoderm by "budding off" rostrally as somitomeres , or whorls of paraxial mesoderm cells, compact and separate into discrete bodies.