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Docetaxel (DTX or DXL), sold under the brand name Taxotere among others, is a chemotherapy medication used to treat a number of types of cancer. [6] This includes breast cancer, head and neck cancer, stomach cancer, prostate cancer and non-small-cell lung cancer. [7]
A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, the frequency and duration of treatments, and other considerations.In modern oncology, many regimens combine several chemotherapy drugs in combination chemotherapy.
Female patients of reproductive potential should use effective contraception during chemotherapy and for a few months after the last dose (e.g. 6 month for doxorubicin [118]). In males previously having undergone chemotherapy or radiotherapy, there appears to be no increase in genetic defects or congenital malformations in their children ...
Mechanism of action of taxanes. The principal mechanism of action of the taxane class of drugs is the disruption of microtubule function. Microtubules are essential to cell division, and taxanes stabilize GDP-bound tubulin in the microtubule, thereby inhibiting the process of cell division as depolymerization is prevented.
A Canadian woman allegedly attempted to smuggle 22 pounds of methamphetamine wrapped as Christmas presents through a New Zealand airport on Sunday, Dec. 8. According to a news release from the New ...
By conducting a meta-analysis of four large breast cancer trials including nearly 3,000 patients, the researchers have discovered that an abnormality on chromosome 17, called CEP17, is associated with a worse outcome for patients, but also that its presence is a highly significant indicator that the tumor will respond to anthracyclines. [12]
A Wisconsin man who faked his own drowning and left his wife and three children to go to Eastern Europe is in police custody, online records show.. Ryan Borgwardt, 45, was booked into the Green ...
LAGUNA NIGUEL, Calif. (AP) — Freddie Freeman’s historic walk-off grand slam ball from Game 1 of the World Series has sold for $1.56 million at auction.. The bidding at SCP Auctions went into ...
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