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Angiogenesis is the physiological process through which new blood vessels form from pre-existing vessels, [1] [2] [3] formed in the earlier stage of vasculogenesis. Angiogenesis continues the growth of the vasculature mainly by processes of sprouting and splitting, but processes such as coalescent angiogenesis , [ 4 ] vessel elongation and ...
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. [ 1 ] [ 2 ] It includes the cardiovascular system , or vascular system , that consists of the heart and blood vessels (from Greek kardia meaning heart , and Latin vascula meaning vessels ).
Vasculogenesis occurs during embryonic development of the circulatory system. Specifically, around blood islands, which first arise in the mesoderm of the yolk sac at 3 weeks of development. [5] Vasculogenesis can also arise in the adult organism from circulating endothelial progenitor cells (derivatives of stem cells). These cells are able to ...
Blood vessels transport blood cells, nutrients, and oxygen to most of the tissues of a body. They also take waste and carbon dioxide away from the tissues. [2] Some tissues such as cartilage, epithelium, and the lens and cornea of the eye are not supplied with blood vessels and are termed avascular.
A process called coalescent angiogenesis [11] [12] is considered the opposite of intussusceptive angiogenesis. During coalescent angiogenesis capillaries fuse and form larger vessels to increase blood flow and circulation. Several other modes of angiogenesis have been described, such as sprouting angiogenesis, vessel co-option and vessel ...
The opposite process occurs when the blood leaves the capillaries and enters the venules, where the blood pressure drops due to an increase in flow rate. Arterioles receive autonomic nervous system innervation and respond to various circulating hormones in order to regulate their diameter. Retinal vessels lack a functional sympathetic ...
A scanning electron microscope (SEM) image of a normal red blood cell (left), a platelet (middle), and a white blood cell (right) One microliter of blood contains: 4.7 to 6.1 million (male), 4.2 to 5.4 million (female) erythrocytes: [13] Red blood cells contain the blood's hemoglobin and distribute oxygen.
Hemodynamics explains the physical laws that govern the flow of blood in the blood vessels. Blood flow ensures the transportation of nutrients, hormones, metabolic waste products, oxygen, and carbon dioxide throughout the body to maintain cell-level metabolism, the regulation of the pH, osmotic pressure and temperature of the whole body, and ...