Search results
Results From The WOW.Com Content Network
Haloperidol decanoate is provided in the form of 50 or 100 mg/mL oil solution of sesame oil and benzyl alcohol in ampoules or pre-filled syringes. [ 6 ] [ 7 ] [ 9 ] Its elimination half-life after multiple doses is 21 days.
The IUPAC name of haloperidol decanoate is [4-(4-chlorophenyl)-1-[4-(4-fluorophenyl)-4-oxobutyl]piperidin-4-yl] decanoate. Topical formulations of haloperidol should not be used as treatment for nausea because research does not indicate this therapy is more effective than alternatives. [39]
Haloperidol decanoate, an antipsychotic ester. An antipsychotic ester is an ester of an antipsychotic . [ 1 ] They are used clinically as prodrugs to increase fat solubility and thereby prolong duration when antipsychotics are used as depot injectables .
Iloperidone is indicated for the treatment of schizophrenia and mania or mixed episodes in bipolar I disorder. [2] [3] In a 2013 study in a comparison of 15 antipsychotic drugs in effectivity in treating schizophrenic symptoms, iloperidone demonstrated mild effectiveness — as effective as lurasidone, and 13 to 15% less effective than ziprasidone, chlorpromazine, and asenapine. [4]
Flupentixol decanoate: Depixol: Typical: Viscoleo b: 10–200 mg/2–4 weeks: 4–10 days: 8 days: 17 days: 7.2–9.2 [4] [5] Fluphenazine decanoate: Prolixin Decanoate: Typical: Sesame oil: 12.5–100 mg/2–5 weeks: 1–2 days: 1–10 days: 14–100 days: 7.2–9.0 [6] [7] [8] Fluphenazine enanthate: Prolixin Enanthate: Typical: Sesame oil ...
Fluphenazine, sold under the brand name Prolixin among others, is a high-potency typical antipsychotic medication. [2] It is used in the treatment of chronic psychoses such as schizophrenia, [2] [3] and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine. [4]
Trifluperidol is a typical antipsychotic of the butyrophenone chemical class.It has general properties similar to those of haloperidol, but is considerably more potent by weight, and causes relatively more severe side effects, especially tardive dyskinesia and other extrapyramidal effects.
According to some authors, organyl derivatives of acidic hydrogen of other acids are esters as well (e.g. amides), but not according to the IUPAC. [ 1 ] An example of an ester formation is the substitution reaction between a carboxylic acid ( R−C(=O)−OH ) and an alcohol (R'OH), forming an ester ( R−C(=O)−O−R' ), where R and R′ are ...