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Treatment depends on the type and cause of the hemolytic anemia. [2] Symptoms of hemolytic anemia are similar to other forms of anemia (fatigue and shortness of breath), but in addition, the breakdown of red cells leads to jaundice and increases the risk of particular long-term complications, such as gallstones [4] and pulmonary hypertension. [5]
Spur cell hemolytic anemia: Spur cell hemolytic anemia is a form of hemolytic anemia that results when free cholesterol binds to the red blood cell's membrane increasing its surface area, causing later deformities such as rough or thorny projections on the erythrocyte named acanthocytes. This condition is caused by the deceased liver's ...
Associated with SLE or other collagen-vascular disorders. [2] Secondary to viral infection. [2] Cold antibody autoimmune hemolytic anemia [2] Paroxysmal cold hemoglobinuria [2] Drug-induced autoimmune hemolytic anemia [2] Alloimmune hemolytic anemia [1] Hemolytic disease of the newborn (HDN) [1] Rh disease (Rh D) [1] ABO hemolytic disease of ...
Red blood cells normally survive an average of about 120 days, becoming damaged (their oxygen-carrying capacity becomes compromised) as they age.
A red blood cell in a hypotonic solution, causing water to move into the cell A red blood cell in a hypertonic solution, causing water to move out of the cell. Hemolysis or haemolysis (/ h iː ˈ m ɒ l ɪ s ɪ s /), [1] also known by several other names, is the rupturing of red blood cells (erythrocytes) and the release of their contents into surrounding fluid (e.g. blood plasma).
Hexokinase deficiency manifests is associated with chronic nonspherocytic hemolytic anemia. [3] Hemolytic anemia seems to be the only clinical sign of hexokinase deficiency. [4] In 1967 the first case of hexokinase deficiency was described by Valentine et al, [5] since then, less than 50 cases have been reported. [6]
Alloimmune hemolytic anemia Hemolytic disease of the newborn (HDN) Rh disease (Rh D) ABO hemolytic disease of the newborn; Anti-Kell hemolytic disease of the newborn; Rhesus c hemolytic disease of the newborn; Rhesus E hemolytic disease of the newborn; Other blood group incompatibility (RhC, Rhe, Kid, Duffy, MN, P and others) Drug induced ...
Diagnosis is made by first ruling out other causes of hemolytic anemia, such as G6PD, thalassemia, sickle-cell disease. Clinical history is also important to elucidate any underlying illness or medications that may have led to the disease. [citation needed] Laboratory investigations are carried out to determine the etiology of the disease.