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Boric acid is only marginally more toxic to most lifeforms than normal table salt, with exposure in humans and other mammals widely regarded as being safe. Its use as an insecticide in malarial control (instead of compounds which demonstrate high levels of mammalian toxicity or carcinogenicity ) is thus seen as advantageous.
Cypermethrin is very toxic to cats which cannot tolerate the therapeutic doses for dogs. [6] This is associated with UGT1A6 deficiency in cats, the enzyme responsible for metabolizing cypermethrin. As a consequence, cypermethrin remains much longer in the cat's organs than in dogs or other mammals and can be fatal in large doses.
Boric acid is a weak acid, with pK a (the pH at which buffering is strongest because the free acid and borate ion are in equal concentrations) of 9.24 in pure water at 25 °C. But apparent p K a is substantially lower in swimming pool or ocean waters because of interactions with various other molecules in solution.
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The symptoms of poisoning vary depending on substance, the quantity a dog has consumed, the breed and size of the mammal.A common list of symptoms are digestion problems, such as vomiting, diarrhea, or blood in stool; bruising and bleeding gums, nose, or inside the ear canal; behavioral changes, such as lethargy, hyperactivity, and seizures; unusual items found in the dog's stool.
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For example, boric acid was widely used as a food preservative from the 1870s to the 1920s, [10] [11] but was banned after World War I due to its toxicity, as demonstrated in animal and human studies.
Boric acid is not a bait in the dry form, but rather broadcast as a dust, that is both a toxin and a desiccant. Boric acid is often formulated into a paste. Roach attractants are mixed with the boric acid. It is similar in consistency to toothpaste. Boric acid roach baits consist of a proprietary blend of attractants.