Search results
Results From The WOW.Com Content Network
General schema showing the relationships of the genome, transcriptome, proteome, and metabolome . A proteome is the entire set of proteins that is, or can be, expressed by a genome, cell, tissue, or organism at a certain time. It is the set of expressed proteins in a given type of cell or organism, at a given time, under defined conditions.
The transcriptome can be seen as a subset of the proteome, that is, the entire set of proteins expressed by a genome. However, the analysis of relative mRNA expression levels can be complicated by the fact that relatively small changes in mRNA expression can produce large changes in the total amount of the corresponding protein present in the cell.
General schema showing the relationships of the genome, transcriptome, proteome, and metabolome Main articles: Omics and Human proteome project The English-language neologism omics informally refers to a field of study in biology ending in -omics , such as genomics, proteomics or metabolomics .
Proteomics is an interdisciplinary domain that has benefited greatly from the genetic information of various genome projects, including the Human Genome Project. [4] It covers the exploration of proteomes from the overall level of protein composition, structure, and activity, and is an important component of functional genomics .
For example, the genome contains the ORFeome, which gives rise to the transcriptome, which is translated to the proteome. Other terms are overlapping and refer to the structure and/or function of a subset of proteins (e.g. glycome, kinome). An omicist is a scientist who studies omeomics, cataloging all the “omics” subfields. [1]
The related suffix -ome is used to address the objects of study of such fields, such as the genome, proteome or metabolome respectively. The suffix -ome as used in molecular biology refers to a totality of some sort; it is an example of a "neo-suffix" formed by abstraction from various Greek terms in -ωμα , a sequence that does not form an ...
General schema showing the relationships of the genome, transcriptome, proteome, and metabolome (lipidome, glycome). The metabolome refers to the complete set of small-molecule chemicals found within a biological sample. [1] The biological sample can be a cell, a cellular organelle, an organ, a tissue, a tissue extract, a biofluid or an entire ...
Multiomics, multi-omics, integrative omics, "panomics" or "pan-omics" is a biological analysis approach in which the data sets are multiple "omes", such as the genome, proteome, transcriptome, epigenome, metabolome, and microbiome (i.e., a meta-genome and/or meta-transcriptome, depending upon how it is sequenced); [1] [2] [3] in other words ...