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Drug-induced gingival enlargement (DIGE), also referred to as drug-induced gingival hyperplasia (DIGH) or drug-induced gingival overgrowth (DIGO), [1] is a side effect of many systemic medications for which the Gingervae are not the target receptor.
Gingival enlargement has a multitude of causes. The most common is chronic inflammatory gingival enlargement, when the gingivae are soft and discolored. This is caused by tissue edema and infective cellular infiltration caused by prolonged exposure to bacterial plaque, and is treated with conventional periodontal treatment, such as scaling and root planing.
It can be used as either monotherapy or combination therapy for the management of hypertension or coronary artery disease. Amlodipine can be administered to adults and to children 6–17 years of age. [7] Calcium channel blockers, including amlodipine, may provide greater protection against stroke than beta blockers.
Gum disease is the most common oral disease, with studies estimating that up to 80% of Americans have dealt with periodontal disease at some point during their lives. The prevalence of gum disease ...
The American Academy of Pediatrics recommends waiting until age 5 to introduce gum to children. This is usually the age when children can chew well, understand the concept of spitting and know not ...
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Drug-related gingival hyperplasia is a cutaneous condition characterized by enlargement of the gums noted during the first year of drug treatment. [1] Although the mechanism of drug related gingival hyperplasia is not well understood, some risk factors for the condition include the duration of drug use and poor oral hygiene. [2]
Thus they are commonly present in many people's homes. In young children one pill may cause serious health problems and potentially death. [8] The calcium channel blocker that caused the greatest number of deaths in 2010 in the United States was verapamil. [2] This agent is believed to cause more heart problems than many of the others. [2]