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Atherosclerosis is characterized by the build-up of plaque inside your blood vessels. It can lead to stenosis, which is a narrowing of your artery walls. Plaque is a fatty substance made up of:
"Dental plaque is a sticky film of bacteria, while arterial plaque is a complex buildup of cholesterol, fat, calcium and cellular debris on artery walls," explains Dr. Rigved Tadwalkar, MD, a ...
"Lipid-rich plaques build up over time and can decrease blood flow through the blood vessel, or the plaque can rupture, causing a blood clot which shuts down the blood vessel and restricts blood ...
The fibro-lipid (fibro-fatty) plaque is characterized by an accumulation of lipid-laden cells underneath the intima of the arteries, typically without narrowing the lumen due to compensatory expansion of the bounding muscular layer of the artery wall. Beneath the endothelium, there is a "fibrous cap" covering the atheromatous "core" of the plaque.
Smaller arteries carry blood supply from the popliteal artery to the calf and into the foot. [4] Blockages caused by plaque build-up or atherosclerosis in any of these arteries can reduce leg blood circulation, causing leg pain that may interfere with daily life. [4] Standard popliteal bypass surgery involves the bypass of the popliteal artery. [5]
The plaque forms and thickens the inner layer of the artery, or intima, hence the name of the procedure which simply means removal of part of the internal layers of the artery. An alternative procedure is carotid stenting , which can also reduce the risk of stroke for some patients.