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The macrolide ring is the lactone (cyclic ester) at upper left. Clarithromycin Roxithromycin. Macrolides are a class of mostly natural products with a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered.
ATC code J01 Antibacterials for systemic use is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products.
Pages in category "Macrolide antibiotics" The following 45 pages are in this category, out of 45 total. This list may not reflect recent changes. A. Aigialomycin D;
Carrimycin is a macrolide antibiotic.It was approved by the National Medical Products Administration of China in 2019. [1] It is approved for the treatment of acute tracheal bronchitis caused by Haemophilus influenzae, Streptococcus pneumoniae, and for the treatment of acute sinusitis caused by S. pneumoniae, H. influenzae, Streptococcus pyogenes, Moraxella catarrhalis, and Staphylococcus. [2]
Erythromycin, a macrolide antibiotic, is one of many naturally occurring macrocycles. [1] Macrocycles are often described as molecules and ions containing a ring of twelve or more atoms. Classical examples include the crown ethers, calixarenes, porphyrins, and cyclodextrins. Macrocycles describe a large, mature area of chemistry. [2]
Macrolide antibiotics (1 C, 45 P) Pages in category "Macrolides" The following 36 pages are in this category, out of 36 total.
Bacteria have a system that allows tetracyclines to be transported into the cell, whereas human cells do not. Human cells therefore are spared the effects of tetracycline on protein synthesis. [1] Tetracyclines retain an important role in medicine, although their usefulness has been reduced with the onset of antibiotic resistance. [2]
Azalides such as azithromycin are a class of macrolide antibiotics that were originally manufactured in response to the poor acid stability exhibited by original macrolides (erythromycin). [1] Following the clinical overuse of macrolides and azalides, ketolides have been developed to combat surfacing macrolide-azalide resistance among ...