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On one hand, this agent offers up to a 95% response rate as part of an interferon-free treatment regimen for hepatitis C. Generally speaking, it is more effective and better tolerated than alternative treatments. Unfortunately, the current per pill cost—$1,000—results in an $84,000 treatment course, creating barriers to therapy for many.
Peginterferon alfa-2a is a long acting interferon. Interferons are proteins released in the body in response to viral infections . Interferons are important for fighting viruses in the body, for regulating reproduction of cells , and for regulating the immune system.
A 2013 meta-analysis over Clinical Infectious Diseases noted the combination-treatment to be safe as well as effective for children and adolescents; other meta-analyses had noted the same for adult population. [9] A 2012 meta-analysis had found PEGylated interferon alfa-2a to be the more effective variant for treatment-naive patients. [10]
Peginterferon beta-1a, sold under the brand name Plegridy, is medication used to treat multiple sclerosis. [ 4 ] [ 5 ] The most common side effects include headache, muscle pain, joint pain, influenza (flu)-like symptoms, pyrexia (fever), chills, asthenia (weakness), and erythema (reddening of the skin), pain or pruritus (itching) at the ...
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Pegylated interferon (PEG-IFN) is a class of medication that includes three different drugs as of 2012: [1]. Pegylated interferon-alpha-2a; Pegylated interferon-alpha-2b ...
Peginterferon alfa-2a (Pegasys) – PEGylated interferon alpha for use in the treatment of chronic hepatitis C and hepatitis B (Hoffmann-La Roche, 2002) Peginterferon alfa-2b (PegIntron) – PEGylated interferon alpha for use in the treatment of chronic hepatitis C and hepatitis B (Schering-Plough/Enzon, 2000)
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