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Uromune, also known by its developmental code name MV-140, is a polyvalent bacterial vaccine which is used and is being developed for prevention of recurrent urinary tract infections (UTIs). [ 1 ] [ 2 ] [ 3 ] In clinical studies , it has been found to reduce total number of UTIs by about 70%, to increase UTI-free rates from around 25% to 57% ...
A urinary tract infection (UTI) is an infection that affects a part of the urinary tract. [1] Lower urinary tract infections may involve the bladder ( cystitis ) or urethra ( urethritis ) while upper urinary tract infections affect the kidney ( pyelonephritis ). [ 10 ]
A 2012 Cochrane review found that methenamine was effective in the prevention of UTIs. [12] The relative risk of symptomatic UTI was 0.24 and of bacteriuria was 0.56. [12] In the case of short-term treatment (≤1 week), the relative risk of symptomatic UTI was 0.14. [12]
Urinary tract infection in pediatric patients is a significant clinical issue, affecting approximately 7% of fevered infants and children. [43] If left untreated, the infection can ascend from the bladder to the kidneys, resulting in acute pyelonephritis, which leads to hypertension , kidney scarring , and end-stage kidney disease .
A single dose covers the whole perioperative risk period - even if the operation is delayed or long-lasting - and with regard to respiratory and urinary tract infections Repeat administrations for prophylaxis are not necessary, so that additional doses are less likely to be forgotten (an advantage of practical value in a busy working situation ...
[4] [10] [11] [12] It is used as an alternative to antibiotics to prevent urinary tract infections (UTIs) and is sold under the brand names Hiprex, Urex, and Urotropin, among others. [4] [10] [12] As the mandelic acid salt (methenamine mandelate) or the hippuric acid salt (methenamine hippurate), [13] it is used for the treatment of urinary ...