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Salicylate poisoning, also known as aspirin poisoning, is the acute or chronic poisoning with a salicylate such as aspirin. [1] The classic symptoms are ringing in the ears, nausea, abdominal pain, and a fast breathing rate. [1] Early on, these may be subtle, while larger doses may result in fever.
Physostigmine, an acetylcholinesterase inhibitor, can be used to treat glaucoma and delayed gastric emptying.Because it enhances the transmission of acetylcholine signals in the brain and can cross the blood–brain barrier, physostigmine salicylate is used to treat anticholinergic poisoning (that is, poisoning by substances that interfere with the transmission of acetylcholine signaling, such ...
Salicylate overdose can occur in people without salicylate sensitivity, and can be deadly if untreated. For more information, see aspirin poisoning . Salicylates are derivatives of salicylic acid that occur naturally in plants and serve as a natural immune hormone and preservative , protecting the plants against diseases , insects , fungi , and ...
An antidote is a substance that can counteract a form of poisoning. [1] ... Beta blocker poisoning and calcium channel blocker poisoning ... Aspirin, TCAs with a wide ...
Acetylcysteine is the antidote for paracetamol toxicity. Acetylcysteine, also called N-acetylcysteine or NAC, works to reduce paracetamol toxicity by replenishing body stores of the antioxidant glutathione. Glutathione reacts with the toxic NAPQI metabolite so that it does not damage cells and can be safely excreted. [67]
Side effects include skin irritation, and salicylate poisoning. [2] Salicylate poisoning tends to only occur when applied to a large area and in children. [2] Use is thus not recommended in children less than two years old. [2] It comes in a number of different strengths. [3] It is on the World Health Organization's List of Essential Medicines.
And they suffered some of the telltale signs of aconite poisoning, lapsing into weakness less than a hour after drinking the tea and having their heart rhythms become so abnormal that doctors had ...
The diagnosis of poisoning usually involves measurement of plasma salicylate, the active metabolite of aspirin, by automated spectrophotometric methods. Plasma salicylate levels in general range from 30 to 100 mg/L after usual therapeutic doses, 50–300 mg/L in people taking high doses and 700–1400 mg/L following acute overdose.