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2. Effects of nicotine on human brain development - Wikipedia

   en.wikipedia.org/wiki/Effects_of_nicotine_on...

   When nicotine enters the brain it stimulates, among other activities, the midbrain dopaminergic neurons situated in the ventral tegmental area and pars compacta. [12] Nicotine negatively affects the prefrontal cortex of the developing brain. Prenatal nicotine exposure can result in long-term adverse effects to the developing brain.

3. Nicotine - Wikipedia

   en.wikipedia.org/wiki/Nicotine

   Nicotine use as a tool for quitting smoking has a good safety history. [36] Animal studies suggest that nicotine may adversely affect cognitive development in adolescence, but the relevance of these findings to human brain development is disputed. [37] [27] At low amounts, it has a mild analgesic effect. [38]

4. Epigenetic effects of smoking - Wikipedia

   en.wikipedia.org/wiki/Epigenetic_effects_of_smoking

   It is thought that epigenetic changes that arise from smoking cigarettes or exposure to cigarette smoke play a role in the development of these conditions. Epigenetic modifications to the genome, including histone modifications, DNA methylation, and the modulation of RNAi, are major epigenetic events used to modulate gene expression.

5. Microdosing nicotine: Could it actually be good for your ...

   www.aol.com/lifestyle/microdosing-nicotine-could...

   But nicotine does have an effect on one’s brain. “At low concentrations, nicotine does decrease anxiety, whereas at high doses it increases anxiety,” Bhatnagar tells Yahoo. “It can also ...

6. Study: Smoking permanently shrinks the brain, driving up ...

   www.aol.com/study-smoking-permanently-shrinks...

   The findings, published in Biological Psychiatry: Global Open Science, were a result of comparing 32,094 smokers' smoking history, brain imaging, genetic predisposition and other health data points.

7. Alpha-7 nicotinic receptor - Wikipedia

   en.wikipedia.org/wiki/Alpha-7_nicotinic_receptor

   The Recent work has demonstrated a potential role in reducing inflammatory neurotoxicity in stroke, myocardial infarction, sepsis, and Alzheimer's disease. [4] [5] [6]The α7 receptor is highly implicated in the efficacy of Varenicline for smoking cessation therapy significantly more than α4β2 which is responsible for Nicotine's rewarding effects.

8. Avoiding This Type Of Drink Could Help Prevent Dementia—Plus ...

   www.aol.com/doctors-share-14-things-lower...

   Avoid smoking. Smoking has been linked to dementia because it can increase the risk of problems with the heart and blood vessels, the Alzheimer’s Society says. Toxins in cigarettes also cause ...

9. Alpha-4 beta-2 nicotinic receptor - Wikipedia

   en.wikipedia.org/wiki/Alpha-4_beta-2_nicotinic...

   A 2015 review noted that stimulation of the α4β2 nicotinic receptor in the brain is responsible for certain improvements in attentional performance; [4] among the nicotinic receptor subtypes, nicotine has the highest binding affinity at the α4β2 receptor (k i =1 nM), which is also the primary biological target that mediates nicotine's ...