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  2. Intracardiac injection - Wikipedia

    en.wikipedia.org/wiki/Intracardiac_injection

    The practice of intracardiac injection originated in the 1800s. It was commonly performed during the 1960s, as it was considered the fastest way to get medication to the heart. The practice began declining during the 1970s as more reliable delivery methods (i.e., intravenous, endotracheal, and intraosseous) came into use. Around that time ...

  3. Intraosseous infusion - Wikipedia

    en.wikipedia.org/wiki/Intraosseous_infusion

    Intraosseous infusion (IO) is the process of injecting medication, fluids, or blood products directly into the bone marrow; [1] this provides a non-collapsible entry point into the systemic venous system. [2] The intraosseous infusion technique is used to provide fluids and medication when intravenous access is not available or not feasible.

  4. Cold shock response - Wikipedia

    en.wikipedia.org/wiki/Cold_shock_response

    The cold water can cause heart attack due to severe vasoconstriction, [2] where the heart has to work harder to pump the same volume of blood throughout the arteries. For people with pre-existing cardiovascular disease , the additional workload can result in myocardial infarction and/or acute heart failure , which ultimately may lead to a ...

  5. Adrenaline - Wikipedia

    en.wikipedia.org/wiki/Adrenaline

    Adrenaline, also known as epinephrine, is a hormone and medication [10] [11] which is involved in regulating visceral functions (e.g., respiration). [10] [12] It appears as a white microcrystalline granule. [13] Adrenaline is normally produced by the adrenal glands and by a small number of neurons in the medulla oblongata. [14]

  6. Epinephrine autoinjector - Wikipedia

    en.wikipedia.org/wiki/Epinephrine_autoinjector

    An epinephrine autoinjector (or adrenaline autoinjector, also known by the trademark EpiPen) is a medical device for injecting a measured dose or doses of epinephrine (adrenaline) by means of autoinjector technology. It is most often used for the treatment of anaphylaxis. The first epinephrine autoinjector was brought to market in 1983.

  7. Adrenal medulla - Wikipedia

    en.wikipedia.org/wiki/Adrenal_medulla

    Notable effects of adrenaline (epinephrine) and noradrenaline (norepinephrine) include increased heart rate and blood pressure, blood vessel constriction in the skin and gastrointestinal tract, smooth muscle (bronchiole and capillary) dilation, and increased metabolism, all of which are characteristic of the fight-or-flight response. [1]

  8. Yes, You Can Visit the 'When Calls the Heart' Filming ... - AOL

    www.aol.com/hope-valley-calls-heart-isnt...

    When Calls the Heart fans are able to visit Hope Valley as part of the Hearties Family Reunion.The three-day event features meet-and-greets with the cast, meals from Abigail's Cafe, and a behind ...

  9. Dale's principle - Wikipedia

    en.wikipedia.org/wiki/Dale's_principle

    The source that Eccles referred to was a lecture published by Dale in 1934, called Pharmacology and nerve endings, describing some of the early research into the physiology of neurotransmission. [3] At that time, only two chemical transmitters were known, acetylcholine and noradrenaline (then thought to be adrenaline ). [ 4 ]