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A tablet press in operation An old rotary tablet press. A tablet press is a mechanical device that compresses powder into tablets of uniform size and weight. A tablet press can be used to manufacture tablets of a wide variety of materials, including pharmaceuticals, nutraceuticals, cleaning products, industrial pellets and cosmetics.
The rotary press itself is an evolution of the cylinder press, also patented by William Nicholson, invented by Beaucher of France in the 1780s and by Friedrich Koenig in the early 19th century. [ 1 ] [ 2 ] Rotary drum printing was invented by Josiah Warren in 1832, [ 3 ] whose design was later imitated by Richard March Hoe in 1843. [ 4 ]
The compression is done either by a single-punch machine (also called stamping press, achieves an output of approximately 200 tablets per minute, making it ideal for manufacturing small batches of tablets) or by a multi-station machine (rotary press). The tablet press is a high-speed mechanical device.
The upper and lower punches compress the tablet in two steps as they travel across heavy compression rolls. The tablet is then ejected from the cavity and the process repeats. At full speed, a typical press can make over 250,000 tablets per hour. Reason Animation shows the complex, multi-step process of tablet pressing in a convenient view.
Softgels are filled at the same time as they are produced and sealed on the rotary die of a fully automatic machine. Capsule fill weight is a critical attribute in encapsulation and various real-time fill weight monitoring techniques such as near-infrared spectroscopy (NIR) and vibrational spectroscopy are used, as well as in-line weight checks ...
Tablet formulations are designed and tested using a laboratory machine called a Tablet Compaction Simulator or Powder Compaction Simulator. This is a computer controlled device that can measure the punch positions, punch pressures, friction forces, die wall pressures, and sometimes the tablet internal temperature during the compaction event.
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Rotary letterpress machines are still used on a wide scale for printing self-adhesive and non-self-adhesive labels, tube laminate, cup stock, etc. The printing quality achieved by a modern letterpress machine with UV curing is on par with flexo presses. It is more convenient and user friendly than a flexo press.