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The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, carboxy tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH). When the protein is translated from messenger RNA, it is created from N-terminus to C-terminus. The ...
For algorithms and data structures not necessarily mentioned here, see list of algorithms and list of data structures. This list of terms was originally derived from the index of that document, and is in the public domain, as it was compiled by a Federal Government employee as part of a Federal Government work. Some of the terms defined are:
The C-terminal carboxylate group of a polypeptide can also be modified, e.g., Fig. 3 C-terminal amidation. amination (see Figure) The C-terminus can also be blocked (thus, neutralizing its negative charge) by amination. glycosyl phosphatidylinositol (GPI) attachment
Map functions can be and often are defined in terms of a fold such as foldr, which means one can do a map-fold fusion: foldr f z . map g is equivalent to foldr (f . g) z . The implementation of map above on singly linked lists is not tail-recursive , so it may build up a lot of frames on the stack when called with a large list.
Carboxypeptidase A usually refers to the pancreatic exopeptidase that hydrolyzes peptide bonds of C-terminal residues with aromatic or aliphatic side-chains. Most scientists in the field now refer to this enzyme as CPA1 , and to a related pancreatic carboxypeptidase as CPA2 .
One or more DNA-binding domains are often part of a larger protein consisting of further protein domains with differing function. The extra domains often regulate the activity of the DNA-binding domain. The function of DNA binding is either structural or involves transcription regulation, with the two roles sometimes overlapping. [citation needed]
By convention, peptide sequences are written N-terminus to C-terminus, left to right (in LTR writing systems). [1] This correlates the translation direction to the text direction, because when a protein is translated from messenger RNA, it is created from the N-terminus to the C-terminus, as amino acids are added to the carboxyl end of the protein.
The term closure is often used as a synonym for anonymous function, though strictly, an anonymous function is a function literal without a name, while a closure is an instance of a function, a value, whose non-local variables have been bound either to values or to storage locations (depending on the language; see the lexical environment section below).