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The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, carboxy tail, C-terminal end, or COOH-terminus) is the end of an amino acid chain (protein or polypeptide), terminated by a free carboxyl group (-COOH). When the protein is translated from messenger RNA, it is created from N-terminus to C-terminus. The ...
CPA-1 and CPA-2 (and, it is presumed, all other CPAs) employ a zinc ion within the protein for hydrolysis of the peptide bond at the C-terminal end of an amino acid residue. Loss of the zinc leads to loss of activity, which can be replaced easily by zinc, and also by some other divalent metals ( cobalt , nickel ).
Contractive maps are sometimes called Lipschitzian maps. If the above condition is instead satisfied for k ≤ 1, then the mapping is said to be a non-expansive map . More generally, the idea of a contractive mapping can be defined for maps between metric spaces.
A carboxypeptidase (EC number 3.4.16 - 3.4.18) is a protease enzyme that hydrolyzes (cleaves) a peptide bond at the carboxy-terminal (C-terminal) end of a protein or peptide. This is in contrast to an aminopeptidases, which cleave peptide bonds at the N-terminus of proteins. Humans, animals, bacteria and plants contain several types of ...
A signal peptide (sometimes referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a short peptide (usually 16-30 amino acids long) [1] present at the N-terminus (or occasionally nonclassically at the C-terminus [2] or internally) of most newly synthesized proteins that are destined toward the ...
Therefore, compilers will attempt to transform the first form into the second; this type of optimization is known as map fusion and is the functional analog of loop fusion. [2] Map functions can be and often are defined in terms of a fold such as foldr, which means one can do a map-fold fusion: foldr f z . map g is equivalent to foldr (f .
The term closure is often used as a synonym for anonymous function, though strictly, an anonymous function is a function literal without a name, while a closure is an instance of a function, a value, whose non-local variables have been bound either to values or to storage locations (depending on the language; see the lexical environment section below).
The C-terminus domain has been shown experimentally to be required for correct assembly of tight junction barrier function. [20] The C-terminus also interacts with several cytoplasmic proteins of the junctional plaque and interacts with signaling molecules responsible for cell survival. [21] The N-terminus of occludin experimentally has been ...