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Conversely, it was associated with a significant incidence of androgenic side effects, including acne and hirsutism (excessive facial/body hair growth). [38] Other androgenic side effects, such as weight gain, pattern hair loss, and voice deepening, were also reported in some trials, but were excluded from analyses due to insufficient data. [38]
Both testosterone and DHT bind to an androgen receptor; however, DHT has a stronger binding affinity than testosterone and may have more androgenic effect in certain tissues at lower levels. [18] Anabolic effects include growth of muscle mass and strength, increased bone density and strength, and stimulation of linear growth and bone maturation.
Hyperandrogenism, especially high levels of testosterone, can cause serious adverse effects if left untreated. High testosterone levels are associated with other health conditions such as obesity, hypertension, amenorrhea (cessation of menstrual cycles), and ovulatory dysfunction, which can lead to infertility.
Your body creates DHT as a byproduct of testosterone, the main androgen hormone in the male body. You need DHT to develop male features before birth and during adolescence, such as your external ...
DHT binds to androgen receptors in your hair follicles, causing miniaturization and gradual hair loss. With finasteride blocking 5-alpha-reductase, less testosterone is converted into DHT, meaning ...
Side effects of testosterone undecanoate include symptoms of masculinization like acne, increased hair growth, voice changes, hypertension, elevated liver enzymes, hypertriglyceridemia, and increased sexual desire. [11] The drug is a prodrug of testosterone, the biological ligand of the androgen receptor (AR) and hence is an androgen and ...
Although anabolic steroid was originally intended to specifically describe testosterone-derived steroids with a marked dissociation of anabolic and androgenic effect, it is applied today indiscriminately to all steroids with AR agonism-based anabolic effects regardless of their androgenic potency, including even non-synthetic and non ...
[10] [5] It has strong androgenic effects and moderate anabolic effects, which make it useful for producing masculinization and suitable for androgen replacement therapy. [5] Testosterone propionate is a testosterone ester and a relatively short-acting prodrug of testosterone in the body.