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Cholestatic pruritus is the sensation of itch due to nearly any liver disease, but the most commonly associated entities are primary biliary cholangitis, primary sclerosing cholangitis, obstructive choledocholithiasis, carcinoma of the bile duct, cholestasis (also see drug-induced pruritus), and chronic hepatitis C viral infection and other forms of viral hepatitis.
Primary biliary cholangitis (PBC), previously known as primary biliary cirrhosis, is an autoimmune disease of the liver. [1] [2] [3] It results from a slow, progressive destruction of the small bile ducts of the liver, causing bile and other toxins to build up in the liver, a condition called cholestasis.
No effective medical treatment for primary sclerosing cholangitis is known. Its most definitive treatment is a liver transplant, [1] but disease recurrence can occur in 25–30% of cases. [6] PSC is a rare disease and most commonly affects people with IBD. [2]
Find out why itchy skin can be a symptom of the disease. Woman who woke up itching all over her body was diagnosed with pancreatic cancer. Find out why itchy skin can be a symptom of the disease ...
Liver diseases, including conditions such as non-alcoholic fatty liver disease (NAFLD), alcohol-related liver disease (ALD), and viral hepatitis, are significant public health concerns worldwide. In the United States, NAFLD is the most common chronic liver condition, affecting approximately 24% of the population, with the prevalence rising due ...
Finally, any systemic disease that can cause diffuse itching such as lymphoma, liver disease, kidney failure, hypothyroidism, and vitamin A, D, and iron deficiencies may cause anal itching. 14 ...
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