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Working together, biologists James Till and Ernest McCulloch made contributions to stem cell research by demonstrating the existence of multipotent stem cells in 1961. They helped lay the foundation for modern stem cell biology and regenerative medicine through their work while studying the effects of radiation on the bone marrow of mice at the Ontario Cancer Institute in Toronto.
McCulloch was born in Toronto, Ontario, Canada on 27 April 1926, [2] [4] and was educated at Upper Canada College and the University of Toronto. [5] Ernest McCulloch received his MD in 1948 from the University of Toronto. Upon graduation, he began his education in research at the Lister Institute in London, England.
Subsequently, Till chose to work with Ernest McCulloch at the University of Toronto. Thus, the older physician's insight was combined with the younger physicist's rigorous and thorough nature. In the early 1960s, McCulloch and Till started a series of experiments that involved injecting bone marrow cells into irradiated mice. They observed that ...
James G. Fujimoto: Inventing optical coherence tomography. [10] David Huang: Eric A. Swanson: Special Achievement Piet Borst: A scientific career spanning 50 years, mentorship, and leadership [11] 2022 Basic Richard O. Hynes: For discoveries concerning the integrins – key mediators of cell–matrix and cell–cell adhesion in physiology and ...
Johns was born to missionary parents in Sichuan, China.He lived in China until 1926, when political unrest there prompted his parents to return to North America.
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