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Perinatal stroke's severity determines its prognosis. 61% of infants who experienced a perinatal stroke are also diagnosed with cerebral palsy. [4] While, infants with greater stroke severities and involvement of structures such as the precentral gyrus and Wernicke's area have a critical prognosis. [ 39 ]
This is associated with cerebral palsy and is suggestive of a hypercoagulable state as the underlying cause. Cerebral palsy is due to abnormal development or damage occurring to the developing brain. [72] This damage can occur during pregnancy, delivery, the first month of life, or less commonly in early childhood. [72]
Neonatal stroke, similar to a stroke which occurs in adults, is defined as a disturbance to the blood supply of the developing brain in the first 28 days of life. [1] This description includes both ischemic events, which results from a blockage of vessels, and hypoxic events, which results from a lack of oxygen to the brain tissue, as well as some combination of the two.
Congenital diseases are medical conditions that are present at birth that may be associated with or inherited through genes. [16] Examples of congenital cerebrovascular diseases include arteriovenous malformations, germinal matrix hemorrhage, and CADASIL (cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy). [9]
Paralysis is most often caused by damage in the nervous system, especially the spinal cord.Other major causes are stroke, trauma with nerve injury, poliomyelitis, cerebral palsy, peripheral neuropathy, Parkinson's disease, ALS, botulism, spina bifida, multiple sclerosis, and Guillain–Barré syndrome.
An estimated 15% of preterm infants who survive develop cerebral palsy and 27% of the infants who survive experience moderate to severe neurosensory deficits by the time they reach 18–24 months old. [7] Prognosis is very poor when IVH results from intracerebral hemorrhage related to high blood pressure and is even worse when hydrocephalus ...
Many conditions that cause paraplegia or quadriplegia begin as monoplegia. Thus, the diagnosis of spinal paraplegia must also be consulted. In addition, multiple cerebral disorders that cause hemiplegia may begin as monoplegia. [1] Monoplegia is also frequently associated with, and considered to be the mildest form of, cerebral palsy.
Focal cerebral ischemia – A stroke occurring in a localized area that can either be acute or transient. This may be due to a variety of medical conditions such as an aneurysm that causes a hemorrhagic stroke, or an occlusion occurring in the affected blood vessels due to a thrombus (thrombotic stroke) or embolus (embolic stroke). [21]