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  2. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    [43] [44] Prolonged-release melatonin is safe with long-term use of up to 12 months. [11] Although not recommended for long-term use beyond this, [45] low-dose melatonin is generally safer, and a better alternative, than many prescription and over-the-counter sleep aids if a sleeping medication must be used for an extended period of time.

  3. Muscle relaxant - Wikipedia

    en.wikipedia.org/wiki/Muscle_relaxant

    Improving sleep is also beneficial for patients who have fibromyalgia. [19] Muscle relaxants such as tizanidine are prescribed in the treatment of tension headaches. [20] Diazepam and carisoprodol are not recommended for older adults, pregnant women, or people who have depression or for those with a history of drug or alcohol addiction. [21]

  4. Glycine - Wikipedia

    en.wikipedia.org/wiki/Glycine

    Glycine is a required co-agonist along with glutamate for NMDA receptors. In contrast to the inhibitory role of glycine in the spinal cord, this behaviour is facilitated at the glutamatergic receptors which are excitatory. [41] The LD 50 of glycine is 7930 mg/kg in rats (oral), [42] and it usually causes death by hyperexcitability. [citation ...

  5. Sleep deprivation - Wikipedia

    en.wikipedia.org/wiki/Sleep_deprivation

    Sleep deprivation, also known as sleep insufficiency [2] or sleeplessness, is the condition of not having adequate duration and/or quality of sleep to support decent alertness, performance, and health. It can be either chronic or acute and may vary widely in severity.

  6. N-Phenylacetyl-L-prolylglycine ethyl ester - Wikipedia

    en.wikipedia.org/wiki/N-Phenylacetyl-L...

    N-Phenylacetyl-l-prolylglycine ethyl ester is promoted as a nootropic and is a prodrug of cyclic glycine-proline. [a] [2] Other names include the brand name Noopept (Russian: Ноопепт), developmental code GVS-111, and proposed INN omberacetam. [2] [3] [4] Its synthesis was first reported in 1996. [2] It is orally available.

  7. Magnesium is going viral as a natural sleep aid. But is it safe?

    www.aol.com/news/magnesium-going-viral-natural...

    A 2023 systematic review of existing studies on magnesium and sleep health found that there may be an association between magnesium levels and sleep quality, but more research is needed, the study ...