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Gastroesophageal reflux disease (GERD) or gastro-oesophageal reflux disease (GORD) is a chronic upper gastrointestinal disease in which stomach content persistently and regularly flows up into the esophagus, resulting in symptoms and/or complications.
In gastroenterology, esophageal pH monitoring is the current gold standard for diagnosis of gastroesophageal reflux disease (GERD). It provides direct physiologic measurement of acid in the esophagus and is the most objective method to document reflux disease, assess the severity of the disease and monitor the response of the disease to medical or surgical treatment.
Gastroesophageal reflux disease is usually assumed to be caused by inflammation from gastric acid reflux which irritates the mucosa. One study suggests that the pathogenesis of may be cytokine-mediated. [6] Microscopic Slide of Infectious Esophagitis. Infectious esophagitis. Esophagitis happens due to a viral, fungal, parasitic or bacterial ...
It is the major symptom of gastroesophageal reflux disease (GERD). [6] Other common descriptors for heartburn (besides burning) are belching, nausea, squeezing, stabbing, or a sensation of pressure on the chest. The pain often rises in the chest (directly behind the breastbone) and may radiate to the neck, throat, or angle of the arm.
Esophageal inlet patches are well defined areas of mucosa which resemble stomach tissue and are pink or salmon colored. [2] The mucosal surface of an esophageal inlet patch is typically flat, [3] but may be slightly raised or slightly depressed.
There are several classes of drugs for acid-related disorders, such as dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD), or laryngopharyngeal reflux. The World Health Organization gives drugs in these classes the categorization code ATC code A02.
These drugs have emerged as the treatment of choice for acid-related diseases, including gastroesophageal reflux disease (GERD) and peptic ulcer disease. PPIs also can bind to other types of proton pumps such as those that occur in cancer cells and are finding applications in the reduction of cancer cell acid efflux and reduction of ...
Gerd or GERD may refer to: Gerd (given name), a list of people with the given name or nickname; Gerd (moon), a moon of Saturn; Gerd Island, South Orkney Islands, Antarctica; Gastroesophageal reflux disease, a chronic symptom of mucosal damage caused by stomach acid coming up from the stomach into the esophagus
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