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SAAM may affect people after long-term statin use even if they had no previous muscular side effects. [4] A differentiating feature between this and more benign statin side effects is SAAM typically has a late onset. While muscle pain (myalgia) is seen in 9-20% of patients treated with statins, it typically occurs in the first month of treatment.
These side effects have been noted: [14] Most frequent: constipation; Increased plasma triglycerides [15] Intestinal obstruction has been reported in patients with previous bowel surgery who should use colestyramine cautiously. [16] [17] Cholestyramine-induced hyperchloremic metabolic acidosis has also been reported rarely. [18]
Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. [4] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. [4] It is also used to decrease the risk of heart problems in those at high risk. [4] It is taken by mouth. [4]
Common side effects when applied to the skin include burning, itching, and a rash. [1] Common side effects when taken by mouth include vomiting and diarrhea. [1] During pregnancy use in the vagina is safe while other formulations have not been studied in this group. [1] It works by disrupting the cell membrane of the fungal cells. [1]
Rarely (<0.1% of patients), hypersensitivity reactions (rash, angioedema) or myopathy may occur. [3] Cases of muscle problems (myalgia and rhabdomyolysis) have been reported and are included as warnings on the label for ezetimibe. [3] Since NPC1L1 also regulates vitamin K uptake, the use of ezetimibe can lead to side effects in warfarin therapy ...
Maculopapular rash (MPR) is a less-well defined and benign form of drug-induced adverse skin reactions; while not classified in the SCARs group, it shares a similar pathophysiology with SCARs and is caused by some of the same drugs which cause SCARs. [2]
Common symptoms of allergic reaction include hives, rash, swelling of the lips, throat, and tongue, and difficulty breathing or swallowing. ... Side effects aren’t something you’re stuck with.
Common side effects include abdominal pain, nausea, headaches, and muscle pains. [6] Serious side effects may include rhabdomyolysis, liver problems, and diabetes. [6] Use during pregnancy may harm the baby. [6] Like all statins, rosuvastatin works by inhibiting HMG-CoA reductase, an enzyme found in the liver that plays a role in producing ...
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