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Paget's disease of bone is the second most common metabolic bone disorder, after osteoporosis. [37] The overall prevalence and severity of Paget's disease are decreasing; the cause for these changes is unclear. [38] Paget's disease is rare in people less than 55 years of age, [7] and the prevalence increases with age. [38]
An example of a disease that is identified through orthopaedic pathology: Comparison of the human body normally (left) with one that has Paget's disease of bone in the pelvic area (right). The bones become fragile and deformed over time as a result.
Bone dysplasias, including Paget's disease of bone, fibrous dysplasia, enchondromatosis, and hereditary multiple exostoses, increase the risk of osteosarcoma. Li–Fraumeni syndrome (germline TP53 mutation) is a predisposing factor for osteosarcoma development.
Symptoms: May or may not be symptomatic, radiographic finding: Complications: Infection with extractions or abscessed teeth, unnecessary root canals: Usual onset: 20-30 years: Types: Localized, generalized: Causes: Congenital: Diagnostic method: X-ray, CBCT scan, vitality testing of teeth: Differential diagnosis: Paget's disease of bone ...
There are many bone disorders such as osteoporosis, Paget's disease, hypothyroidism. [2] Although there are many forms of bone disorders, they all have one thing in common; abnormalities of specific organs involved, deficiency in vitamin D or low Calcium in diet, which results in poor bone mineralization. [2]
A bone scan or bone scintigraphy / s ɪ n ˈ t ɪ ɡ r ə f i / is a nuclear medicine imaging technique used to help diagnose and assess different bone diseases. These include cancer of the bone or metastasis , location of bone inflammation and fractures (that may not be visible in traditional X-ray images ), and bone infection (osteomyelitis).
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Blade of grass sign (also known as flame sign [1]) is a radiologic sign referring to the lytic fronts seen in the leading edge of the long bone in Paget's disease. [2] It is usually seen as a wedge shaped area of radiolucency in the diaphysis of long bone. [1]